Oncoproteomics: New trends in analytical techniques

Girish Gupta¹, Nikhil Gupta², Mayank Gupta³, Soham Trivedi⁴, Prasad Patil⁵, Vamsi Krishna K⁶, Hipal Gaudani⁷, Gomase V.S.^8
1S.D.S.M. College Palghar, Mumbai
²Sindhu Mahavidyalaya Panchpaoli Nagpur
³Sindhu Mahavidyalaya Panchpaoli Nagpur
⁴V.V.P. Engineering College, Rajkot, Gujrat
⁵Dr. D.Y. Patil ACS College, Pimpri, Pune
⁶Rai foundations College CBD Belapur Navi Mumbai
⁷V.V.P. Engineering College, Rajkot, Gujrat
⁸School of Technology, S.R.T.M. University, Sub-Centre, Latur, 413512, India

Received : -     Accepted : -     Published : 21-12-2009
Volume : 1     Issue : 2       Pages : 5 - 9
Int J Drug Discov 1.2 (2009):5-9
DOI : http://dx.doi.org/10.9735/0975-4423.1.2.5-9

Keywords : Oncoproteomics, Genomics, Proteomics, NMR, MS, GC
Conflict of Interest : None declared

Oncoproteomics is the study of proteins and their interactions in a cancer cell by proteomic technologies and has the potential to revolutionize clinical practice, including cancer diagnosis. Oncoproteomics screening based on proteomic platforms as a complement to histopathology, individualized selection of therapeutic combinations that target the entire cancer-specific protein network, real-time assessment of therapeutic efficacy and toxicity and rational modulation of therapy based on changes in the cancer protein network associated with prognosis and drug resistance. Oncoproteomics refers to the application of proteomic technologies in oncology and parallels the related field of oncogenomics. The challenges ahead and perspectives of oncoproteomics for biomarkers development are also addressed. With a wealth of information that can be applied to a broad spectrum of biomarker research projects serves as a reference for biomarker researchers, scientists working in proteomics and bioinformatics, oncologists, pharmaceutical scientists, biochemists, biologists, and chemists.

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