Obesity in human has been a major concern of attention of scientists, medical professionals and health care providers since last two decades. Gradual rise in prevalence and incidence of obesity in the recent decades around the world has been a leading health problem. In the recent years, there is growing recognition that there are some chemical pollutants in the environment, which alter metabolic set points of homeostatic system in human, thus may result in development of obesity during intrauterine or adult life attributed to disruption of the feeding behavior control mechanism leading to activation of adipogenic pathways. Chemically active derivatives of Organotin compounds, identified in many household utilities such as food and cosmetics etc. has been proposed as one of the important endocrine disruptor chemical responsible for genesis of obesity. This paper reviews the existing evidences of possible role of oaganotin compounds in development of obesity in animal & human studies. Based on the evidences, we strongly supports the hypothesis that endocrines disrupting chemicals (EDC) play a potential role in development of obesity, triggering the adipocytes dysfunction or altered metabolic programming in utero and propose the areas for future research.

Objective: Understanding the psychological, neurobiological & genetic factors underlying BPD and the role of a Forensic Psychology professional in handling a BPD-client. Background: Borderline personality disorder (BPD) is characterized by unusual variability and depth of mood, affecting cognition and interpersonal relationships. This disorder is only recognized by the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (Text Revision) (DSM-IV-TR). Findings: Although there is no specific cause for BPD, it is understood to be the result of a combination of biological vulnerabilities, ways of thinking, and social factors (biopsychosocial model). Cortisol production has been found elevated in the BPD-individuals, indicating a hyperactive Hypothalamic-Pituitary-Adrenal axis in them. This area in brain regulates emotions and integrates thoughts and emotions. Neurotransmitters including serotonin and dopamine have been implicated in the regulation of impulses and aggression and their effects have role a significant role in the development of BPD. The identification and recognition of susceptibility genes (like COMT) and polymorphisms in psychiatric diseases may help to identify individuals at risk, in order to establish an appropriate preventive approach against BPD. People experiencing traumatic life events in childhood are at increased risk of developing BPD. Psychotherapy approaches like dialectical behavior therapy and psychoanalytic psychotherapy is found to be helpful in treating BPD. Forensic criminal evaluations should consider the broad context of symptoms and behavior since it provides essential diagnostic information and key in diagnosing the presence of latent character disorders as seen in antisocial, narcissistic or borderline personality. Conclusion: Forensic psychology professionals while handling persons with BPD and related traits should be educated with personal and professional behavior of clients.